July 20, 2017
Giulia Orazi, a PhD student in the lab, recently published a paper in
mBio describing how co-culture with Pseudomonas aeruginosa renders Staphylococcus aureus much more resistant to the front-line antibiotic vancomycin (an increase in viability of ~2-logs). A mixed culture of P. aeruginosa (green) and S. aureus (ref) on human airway cells is shown here. Giulia's work supports the hypothesis that sideophores and HQNO secreted by P. aeruginosa slows the growth of S. aureus, thereby rendering S. aureus more resistant to this cell-wall targeting antibiotic. These data have important implication for designing therapeutics for complex infections based on single organism, in vivo testing assays. It is difficult to predict how microbes in mixed infections may respond to treatments based on standard microdilution assays.
July 18, 2017
Check out the Journal of Bacteriology for a Special Meeting Section associated with the 6th Conference on Beneficial Microbes sponsored by ASM dedicated to the 6th ASM Conference on Beneficial Microbes, held in Seattle, WA, from 9 to 12 September 2016. The special section contains five minireviews and one original article, and are highlighted by a terrific cover image (shown here). The link is here.
July 16, 2017
The Journal of Bacteriology turned 100 years old in 2016. The editors wrote a series of Classic Spotlights highlighting some key papers over the 100 years of the journal's publications. Curious why we count plates with ~200 colonies? How the Gram stain works? Who kicked off the microbiome revolution? The first report of electron bifurcation? Check out this link: https://goo.gl/LuPy31
July 10, 2017
The Microbial Diversity Course at the MBL starts today! 20 students from around the world will live and breath microbiology for 6-1/2 weeks. Check out the website here: http://www.mbl.edu/microbialdiversity/
On the left are a few pics from the opening reception last night. On the top, Dianne and Jared are telling the students about the history of the class. On the bottom, the students settling into their lab benches.
The Microbial Diversity Course at the MBL starts today! 20 students from around the world will live and breath microbiology for 6-1/2 weeks. Check out the website here: http://www.mbl.edu/microbialdiversity/
On the left are a few pics from the opening reception last night. On the top, Dianne and Jared are telling the students about the history of the class. On the bottom, the students settling into their lab benches.